| Year | Round | Selec | Pick | Surname | Forename | Team | Pos | College | Notes | ||
| 2022 | 1 | 1 | 1 | Walker | Travon | JAC | DE | Georgia | |||
| 2022 | 1 | 2 | 2 | Hutchinson | Aidan | DET | DE | Michigan | |||
| 2022 | 1 | 3 | 3 | Stingley | Derek | HOU | DB | LSU | |||
| 2022 | 1 | 4 | 4 | Gardner | Sauce | NYJ | CB | Cincinnati | |||
| 2022 | 1 | 5 | 5 | Thibodeaux | Kayvon | NYG | LB | Oregon | |||
| 2022 | 1 | 6 | 6 | Ekwonu | Ickey | CAR | OT | N.C. State | |||
| 2022 | 1 | 7 | 7 | Neal | Evan | NYG | OT | Alabama | from Bears via Giants | ||
| 2022 | 1 | 8 | 8 | London | Drake | ATL | WR | USC | |||
| 2022 | 1 | 9 | 9 | Cross | Charles | SEA | OT | Mississippi State | from Broncos via Seahawks | ||
| 2022 | 1 | 10 | 10 | Wilson | Garrett | NYJ | WR | Ohio State | from Seahawks via Jets | ||
| 2022 | 1 | 11 | 11 | Olave | Chris | NO | WR | Ohio State | from Commanders via Saints | ||
| 2022 | 1 | 12 | 12 | Williams | Jameson | DET | WR | Alabama | from Vikings via Lions | ||
| 2022 | 1 | 13 | 13 | Davis | Jordan | PHI | DT | Georgia | from Browns via Texans via Eagles | ||
| 2022 | 1 | 14 | 14 | Hamilton | Kyle | BAL | S | Notre Dame | |||
| 2022 | 1 | 15 | 15 | Green | Kenyon | HOU | OL | Texas A&M | from Dolphins via Eagles via Texans | ||
| 2022 | 1 | 16 | 16 | Dotson | Jahan | WAS | WR | Penn State | from Colts via Eagles via Saints via Commanders | ||
| 2022 | 1 | 17 | 17 | Johnson | Zion | LAC | OL | Boston College | |||
| 2022 | 1 | 18 | 18 | Burks | Treylon | TEN | WR | Arkansas | from Saints via Eagles via Titans | ||
| 2022 | 1 | 19 | 19 | Penning | Trevor | NO | OT | Northern Iowa | from Eagles via Saints | ||
| 2022 | 1 | 20 | 20 | Pickett | Kenny | PIT | QB | Pittsburgh | |||
| 2022 | 1 | 21 | 21 | McDuffie | Trent | KAN | CB | Washington | from Patriots via Chiefs | ||
| 2022 | 1 | 22 | 22 | Walker | Quay | GRE | LB | Georgia | from Raiders via Packers | ||
| 2022 | 1 | 23 | 23 | Elam | Kaiir | BUF | CB | Florida | from Cardinals via Ravens via Bills | ||
| 2022 | 1 | 24 | 24 | Smith | Tyler | DAL | OT | Tulsa | |||
| 2022 | 1 | 25 | 25 | Linderbaum | Tyler | BAL | C | Iowa | from Bills via Ravens | ||
| 2022 | 1 | 26 | 26 | Johnson | Jermaine | NYJ | DE | Florida State | from Titans via Jets | ||
| 2022 | 1 | 27 | 27 | Lloyd | Devin | JAC | LB | Utah | from Buccaneers via Jaguars | ||
| 2022 | 1 | 28 | 28 | Wyatt | Devonte | GRE | DT | Georgia | |||
| 2022 | 1 | 29 | 29 | Strange | Cole | NE | G | Tennessee-Chattanooga | from 49ers via Dolphins via Chiefs via Patriots | ||
| 2022 | 1 | 30 | 30 | Karlaftis | George | KAN | LB | Purdue | |||
| 2022 | 1 | 31 | 31 | Hill | Daxton | CIN | S | Michigan | |||
| 2022 | 1 | 32 | 32 | Cine | Lewis | MIN | S | Georgia | from Rams via Lions via Vikings | ||
| 2022 | 2 | 1 | 33 | Hall | Logan | TB | DE | Houston | from Jaguars via Buccaneers | ||
| 2022 | 2 | 2 | 34 | Watson | Christian | GRE | WR | North Dakota State | from Lions via Vikings via Packers | ||
| 2022 | 2 | 3 | 35 | McCreary | Roger | TEN | CB | Auburn | from Jets via Titans | ||
| 2022 | 2 | 4 | 36 | Hall | Breece | NYJ | RB | Iowa State | from Giants via Jets | ||
| 2022 | 2 | 5 | 37 | Pitre | Jalen | HOU | DB | Baylor | |||
| 2022 | 2 | 6 | 38 | Ebiketie | Arnold | ATL | LB | Penn State | from Panthers via Jets via Giants via Falcons | ||
| 2022 | 2 | 7 | 39 | Gordon | Kyler | CHI | CB | Washington | |||
| 2022 | 2 | 8 | 40 | Mafe | Boye | SEA | LB | Minnesota | from Broncos via Seahawks | ||
| 2022 | 2 | 9 | 41 | Walker | Kenneth | SEA | RB | Michigan State | |||
| 2022 | 2 | 10 | 42 | Booth | Andrew | MIN | CB | Clemson | from Commanders via Colts via Vikings | ||
| 2022 | 2 | 11 | 43 | Robinson | Wan'Dale | NYG | WR | Kentucky | from Falcons via Giants | ||
| 2022 | 2 | 12 | 44 | Metchie | John | HOU | WR | Alabama | from Browns via Texans | ||
| 2022 | 2 | 13 | 45 | Ojabo | David | BAL | LB | Michigan | |||
| 2022 | 2 | 14 | 46 | Paschal | Joshua | DET | DE | Kentucky | from Vikings via Lions | ||
| 2022 | 2 | 15 | 47 | Mathis | Phidarian | WAS | DT | Alabama | from Colts via Commanders | ||
| 2022 | 2 | 16 | 48 | Brisker | Jaquan | CHI | S | Penn State | from Chargers via Bears | ||
| 2022 | 2 | 17 | 49 | Taylor | Alontae | NO | CB | Tennessee | |||
| 2022 | 2 | 18 | 50 | Thornton | Tyquan | NE | WR | Baylor | from Dolphins via Chiefs via Patriots | ||
| 2022 | 2 | 19 | 51 | Jurgens | Cam | PHI | C | Nebraska | |||
| 2022 | 2 | 20 | 52 | Pickens | George | PIT | WR | Georgia | |||
| 2022 | 2 | 21 | 53 | Pierce | Alec | IND | WR | Cincinnati | from Raiders via Packers via Vikings via Colts | ||
| 2022 | 2 | 22 | 54 | Moore | Skyy | KAN | WR | Western Michigan | from Patriots via Chiefs | ||
| 2022 | 2 | 23 | 55 | McBride | Trey | ARI | TE | Colorado State | |||
| 2022 | 2 | 24 | 56 | Williams | Sam | DAL | LB | Mississippi | |||
| 2022 | 2 | 25 | 57 | Goedeke | Luke | TB | G | Central Michigan | from Bills via Buccaneers | ||
| 2022 | 2 | 26 | 58 | Andersen | Troy | ATL | LB | Montana State | from Titans via Falcons | ||
| 2022 | 2 | 27 | 59 | Ingram | Ed | MIN | G | LSU | from Packers via Vikings | ||
| 2022 | 2 | 28 | 60 | Taylor-Britt | Cam | CIN | CB | Nebraska | from Buccaneers via Bills via Bengals | ||
| 2022 | 2 | 29 | 61 | Jackson | Drake | SF | LB | USC | |||
| 2022 | 2 | 30 | 62 | Cook | Bryan | KAN | S | Cincinnati | |||
| 2022 | 2 | 31 | 63 | Cook | James | BUF | RB | Georgia | from Bengals via Bills | ||
| 2022 | 2 | 32 | 64 | Bonitto | Nik | DEN | LB | Oklahoma | from Rams via Broncos | ||
| 2022 | 3 | 1 | 65 | Fortner | Luke | JAC | C | Kentucky | |||
| 2022 | 3 | 2 | 66 | Asamoah | Brian | MIN | LB | Oklahoma | from Lions via Vikings | ||
| 2022 | 3 | 3 | 67 | Ezeudu | Joshua | NYG | G | North Carolina | |||
| 2022 | 3 | 4 | 68 | Emerson | Martin | CLE | CB | Mississippi State | from Texans via Browns | ||
| 2022 | 3 | 5 | 69 | Petit-Frere | Nicholas | TEN | OT | Ohio State | from Jets via Titans | ||
| 2022 | 3 | 6 | 70 | Muma | Chad | JAC | LB | Wyoming | from Panthers via Jaguars | ||
| 2022 | 3 | 7 | 71 | Jones | Velus | CHI | WR | Tennessee | |||
| 2022 | 3 | 8 | 72 | Lucas | Abraham | SEA | OT | Washington State | |||
| 2022 | 3 | 9 | 73 | Woods | Jelani | IND | TE | Virginia | from Commanders via Colts | ||
| 2022 | 3 | 10 | 74 | Ridder | Desmond | ATL | QB | Cincinnati | |||
| 2022 | 3 | 11 | 75 | Harris | Christian | HOU | LB | Alabama | from Broncos via Texans | ||
| 2022 | 3 | 12 | 76 | Jones | Travis | BAL | DT | Connecticut | |||
| 2022 | 3 | 13 | 77 | Raimann | Bernhard | IND | OT | Central Michigan | from Vikings via Colts | ||
| 2022 | 3 | 14 | 78 | Wright | Alex | CLE | DE | UAB | |||
| 2022 | 3 | 15 | 79 | Woods | JT | LAC | S | Baylor | |||
| 2022 | 3 | 16 | 80 | Dulcich | Greg | DEN | TE | UCLA | from Saints via Texans via Broncos | ||
| 2022 | 3 | 17 | 81 | Flott | Cordale | NYG | CB | LSU | from Dolphins via Giants | ||
| 2022 | 3 | 18 | 82 | Malone | DeAngelo | ATL | LB | Western Kentucky | from Colts via Falcons | ||
| 2022 | 3 | 19 | 83 | Dean | Nakobe | PHI | LB | Georgia | |||
| 2022 | 3 | 20 | 84 | Leal | DeMarvin | PIT | DT | Texas A&M | |||
| 2022 | 3 | 21 | 85 | Jones | Marcus | NE | CB | Houston | |||
| 2022 | 3 | 22 | 86 | Willis | Malik | TEN | QB | Liberty | from Raiders via Titans | ||
| 2022 | 3 | 23 | 87 | Thomas | Cameron | ARI | DE | San Diego State | |||
| 2022 | 3 | 24 | 88 | Tolbert | Jalen | DAL | WR | South Alabama | |||
| 2022 | 3 | 25 | 89 | Bernard | Terrel | BUF | LB | Baylor | |||
| 2022 | 3 | 26 | 90 | Parham | Dylan | LV | G | Memphis | from Titans via Raiders | ||
| 2022 | 3 | 27 | 91 | White | Rachaad | TB | RB | Arizona State | |||
| 2022 | 3 | 28 | 92 | Rhyan | Sean | GRE | OL | UCLA | |||
| 2022 | 3 | 29 | 93 | Davis-Price | Tyrion | SF | RB | LSU | |||
| 2022 | 3 | 30 | 94 | Corral | Matt | CAR | QB | Mississippi | |||
| 2022 | 3 | 31 | 95 | Carter | Zachary | CIN | DE | Florida | from Chiefs via Patriots via Panthers | ||
| 2022 | 3 | 32 | 96 | Cross | Nick | IND | S | Maryland | from Rams via Broncos via Colts | ||
| 2022 | 3 | 33 | 97 | Joseph | Kerby | DET | S | Illinois | Compensatory selection | ||
| 2022 | 3 | 34 | 98 | Robinson | Brian | WAS | RB | Alabama | Compensatory selection from Saints via Commanders | ||
| 2022 | 3 | 35 | 99 | Bell | David | CLE | WR | Purdue | Special compensatory selection | ||
| 2022 | 3 | 36 | 100 | Sanders | Myjai | ARI | LB | Cincinnati | Special compensatory selection from Ravens via Cardinals | ||
| 2022 | 3 | 37 | 101 | Ruckert | Jeremy | NYJ | TE | Ohio State | Special compensatory selection from Saints via Eagles via Titans via Jets | ||
| 2022 | 3 | 38 | 102 | Tindall | Channing | MIA | LB | Georgia | Special compensatory selection from 49ers via Dolphins | ||
| 2022 | 3 | 39 | 103 | Chenal | Leo | KAN | LB | Wisconsin | Special compensatory selection | ||
| 2022 | 3 | 40 | 104 | Bruss | Logan | LAR | G | Wisconsin | Special compensatory selection | ||
| 2022 | 3 | 41 | 105 | Gray | Danny | SF | WR | SMU | Special compensatory selection | ||
| 2022 | 4 | 1 | 106 | Otton | Cade | TB | TE | Washington | from Jaguars via Buccaneers | ||
| 2022 | 4 | 2 | 107 | Pierce | Dameon | HOU | RB | Florida | from Seahawks via Browns via Texans | ||
| 2022 | 4 | 3 | 108 | Winfrey | Perrion | CLE | DT | Oklahoma | from Texans via Browns | ||
| 2022 | 4 | 4 | 109 | Bryant | Coby | SEA | CB | Cincinnati | from Jets via Seahawks | ||
| 2022 | 4 | 5 | 110 | Faalele | Daniel | BAL | OT | Minnesota | from Giants via Ravens | ||
| 2022 | 4 | 6 | 111 | Mitchell | Max | NYJ | OT | Louisiana | from Panthers via Jets | ||
| 2022 | 4 | 7 | 112 | Bellinger | Daniel | NYG | TE | San Diego State | from Bears via Giants | ||
| 2022 | 4 | 8 | 113 | Butler | Percy | WAS | S | Louisiana | |||
| 2022 | 4 | 9 | 114 | Belton | Dane | NYG | S | Iowa | from Falcons via Giants | ||
| 2022 | 4 | 10 | 115 | Mathis | Damarri | DEN | CB | Pittsburgh | |||
| 2022 | 4 | 11 | 116 | Uwazurike | Eyioma | DEN | DT | Iowa State | from Seahawks via Broncos | ||
| 2022 | 4 | 12 | 117 | Clemons | Micheal | NYJ | DE | Texas A&M | from Vikings via Jets | ||
| 2022 | 4 | 13 | 118 | Evans | Akayleb | MIN | CB | Missouri | from Browns via Vikings | ||
| 2022 | 4 | 14 | 119 | Armour-Davis | Jalyn | BAL | CB | Alabama | |||
| 2022 | 4 | 15 | 120 | Smith | Brandon | CAR | LB | Penn State | from Saints via Commanders via Panthers | ||
| 2022 | 4 | 16 | 121 | Jones | Jack | NE | CB | Arizona State | from Dolphins via Chiefs via Patriots | ||
| 2022 | 4 | 17 | 122 | White | Zamir | LV | RB | Georgia | from Colts via Vikings via Raiders | ||
| 2022 | 4 | 18 | 123 | Spiller | Isaiah | LAC | RB | Texas A&M | |||
| 2022 | 4 | 19 | 124 | York | Cade | CLE | K | LSU | from Eagles via Texans via Browns | ||
| 2022 | 4 | 20 | 125 | Ezukanma | Erik | MIA | WR | Texas Tech | from Steelers via Dolphins | ||
| 2022 | 4 | 21 | 126 | Farrell | Neil | LV | DT | LSU | from Raiders via Vikings via Raiders | ||
| 2022 | 4 | 22 | 127 | Strong | Pierre | NE | RB | South Dakota State | |||
| 2022 | 4 | 23 | 128 | Kolar | Charlie | BAL | TE | Iowa State | from Cardinals via Ravens | ||
| 2022 | 4 | 24 | 129 | Ferguson | Jake | DAL | TE | Wisconsin | |||
| 2022 | 4 | 25 | 130 | Stout | Jordan | BAL | P | Penn State | from Bills via Ravens | ||
| 2022 | 4 | 26 | 131 | Haskins | Hassan | TEN | RB | Michigan | |||
| 2022 | 4 | 27 | 132 | Doubs | Romeo | GRE | WR | Nevada | |||
| 2022 | 4 | 28 | 133 | Camarda | Jake | TB | P | Georgia | |||
| 2022 | 4 | 29 | 134 | Burford | Spencer | SF | G | Texas-San Antonio | |||
| 2022 | 4 | 30 | 135 | Williams | Joshua | KAN | CB | Fayetteville State University | |||
| 2022 | 4 | 31 | 136 | Volson | Cordell | CIN | G | North Dakota State | |||
| 2022 | 4 | 32 | 137 | Zappe | Bailey | NE | QB | Western Kentucky | from Rams via Texans via Panthers via Patriots | ||
| 2022 | 4 | 33 | 138 | Austin | Calvin | PIT | WR | Memphis | Compensatory selection | ||
| 2022 | 4 | 34 | 139 | Likely | Isaiah | BAL | TE | Coastal Carolina | Compensatory selection | ||
| 2022 | 4 | 35 | 140 | Tom | Zach | GRE | OL | Wake Forest | Compensatory selection | ||
| 2022 | 4 | 36 | 141 | Williams | Damarion | BAL | CB | Houston | Compensatory selection | ||
| 2022 | 4 | 37 | 142 | Durant | Decobie | LAR | CB | South Carolina State | Compensatory selection | ||
| 2022 | 4 | 38 | 143 | Okonkwo | Chigoziem | TEN | TE | Maryland | Compensatory selection | ||
| 2022 | 5 | 1 | 144 | Howell | Sam | WAS | QB | North Carolina | from Jaguars via Panthers via Commanders | ||
| 2022 | 5 | 2 | 145 | Kinnard | Darian | KAN | G | Kentucky | from Lions via Broncos via Seahawks via Chiefs | ||
| 2022 | 5 | 3 | 146 | McFadden | Micah | NYG | LB | Indiana | from Jets via Giants | ||
| 2022 | 5 | 4 | 147 | Davidson | DJ | NYG | DT | Arizona State | |||
| 2022 | 5 | 5 | 148 | Shakir | Khalil | BUF | WR | Boise State | from Texans via Bears via Bills | ||
| 2022 | 5 | 6 | 149 | Turner | Cole | WAS | TE | Nevada | from Panthers via Commanders | ||
| 2022 | 5 | 7 | 150 | Booker | Thomas | HOU | DT | Stanford | from Bears via Texans | ||
| 2022 | 5 | 8 | 151 | Allgeier | Tyler | ATL | RB | BYU | |||
| 2022 | 5 | 9 | 152 | Turner-Yell | Delarrin | DEN | S | Oklahoma | |||
| 2022 | 5 | 10 | 153 | Woolen | Tariq | SEA | CB | Texas-San Antonio | |||
| 2022 | 5 | 11 | 154 | Conner | Snoop | JAC | RB | Mississippi | from Commanders via Eagles via Jaguars | ||
| 2022 | 5 | 12 | 155 | Waletzko | Matt | DAL | OT | North Dakota | from Browns via Cowboys | ||
| 2022 | 5 | 13 | 156 | Ford | Jerome | CLE | RB | Cincinnati | from Ravens via Vikings via Browns | ||
| 2022 | 5 | 14 | 157 | McCollum | Zyon | TB | CB | Sam Houston State | from Vikings via Jaguars via Buccaneers | ||
| 2022 | 5 | 15 | 158 | Smith | Tyreke | SEA | LB | Ohio State | from Dolphins via Patriots via Chiefs via Seahawks | ||
| 2022 | 5 | 16 | 159 | Johnson | Eric | IND | DT | Missouri State | |||
| 2022 | 5 | 17 | 160 | Ogbonnia | Otito | LAC | DT | UCLA | |||
| 2022 | 5 | 18 | 161 | Jackson | D'Marco | NO | LB | Appalachian State | |||
| 2022 | 5 | 19 | 162 | Washington | Montrell | DEN | WR | Samford | from Eagles via Texans via Broncos | ||
| 2022 | 5 | 20 | 163 | Philips | Kyle | TEN | WR | UCLA | from Steelers via Jets via Titans | ||
| 2022 | 5 | 21 | 164 | Williams | Kyren | LAR | RB | Notre Dame | from Patriots via Raiders via Rams | ||
| 2022 | 5 | 22 | 165 | Otomewo | Esezi | MIN | DE | Minnesota | from Raiders via Vikings | ||
| 2022 | 5 | 23 | 166 | Anderson | Tycen | CIN | S | Toledo | from Cardinals via Eagles via Texans via Bears via Bengals | ||
| 2022 | 5 | 24 | 167 | Bland | DaRon | DAL | CB | Fresno State | |||
| 2022 | 5 | 25 | 168 | Jones | Braxton | CHI | OT | Southern Utah State | from Bills via Bears | ||
| 2022 | 5 | 26 | 169 | Chandler | Ty | MIN | RB | North Carolina | from Titans via Raiders via Vikings | ||
| 2022 | 5 | 27 | 170 | Quitoriano | Teagan | HOU | TE | Oregon State | from Buccaneers via Patriots via Texans | ||
| 2022 | 5 | 28 | 171 | Wattenberg | Luke | DEN | C | Washington | from Packers via Broncos | ||
| 2022 | 5 | 29 | 172 | Womack | Samuel | SF | CB | Toledo | |||
| 2022 | 5 | 30 | 173 | McKethan | Marcus | NYG | G | North Carolina | from Chiefs via Ravens via Giants | ||
| 2022 | 5 | 31 | 174 | Robinson | Dominique | CHI | LB | Miami (Ohio) | from Bengals via Bears | ||
| 2022 | 5 | 32 | 175 | Butler | Matthew | LV | DT | Tennessee | from Rams via Raiders | ||
| 2022 | 5 | 33 | 176 | Clark | Damone | DAL | LB | LSU | Compensatory selection | ||
| 2022 | 5 | 34 | 177 | Mitchell | James | DET | TE | Virginia Tech | Compensatory selection | ||
| 2022 | 5 | 35 | 178 | Ridgeway | John | DAL | DT | Arkansas | Compensatory selection | ||
| 2022 | 5 | 36 | 179 | Enagbare | Kingsley | GRE | LB | South Carolina | Compensatory selection from Colts via Broncos via Packers | ||
| 2022 | 6 | 1 | 180 | Araiza | Matt | BUF | P | San Diego State | from Jaguars via Buccaneers via Bills | ||
| 2022 | 6 | 2 | 181 | Johnson | Kyron | PHI | LB | Kansas | from Lions via Eagles | ||
| 2022 | 6 | 3 | 182 | Beavers | Darrian | NYG | LB | Cincinnati | |||
| 2022 | 6 | 4 | 183 | Harris | Kevin | NE | RB | South Carolina | from Texans via Patriots | ||
| 2022 | 6 | 5 | 184 | Lowe | Vederian | MIN | OT | Illinois | from Jets via Vikings | ||
| 2022 | 6 | 6 | 185 | Benford | Christian | BUF | CB | Villanova | from Panthers via Bills | ||
| 2022 | 6 | 7 | 186 | Thomas | Zach | CHI | G | San Diego State | |||
| 2022 | 6 | 8 | 187 | Zakelj | Nick | SF | OT | Fordham | from Broncos via 49ers | ||
| 2022 | 6 | 9 | 188 | Rodriguez | Malcolm | DET | LB | Oklahoma State | from Seahawks via Jaguars via Eagles via Lions | ||
| 2022 | 6 | 10 | 189 | Barno | Amare | CAR | LB | Virginia Tech | from Commanders via Panthers | ||
| 2022 | 6 | 11 | 190 | Shaffer | Justin | ATL | G | Georgia | |||
| 2022 | 6 | 12 | 191 | Nailor | Jalen | MIN | WR | Michigan State | from Ravens via Chiefs via Vikings | ||
| 2022 | 6 | 13 | 192 | Ogletree | Andrew | IND | TE | Youngstown State | from Vikings via Colts | ||
| 2022 | 6 | 14 | 193 | Harper | Devin | DAL | LB | Oklahoma State | from Browns via Cowboys | ||
| 2022 | 6 | 15 | 194 | Jackson | Jordan | NO | DT | Air Force | from Colts via Eagles via Saints | ||
| 2022 | 6 | 16 | 195 | Salyer | Jamaree | LAC | OL | Georgia | |||
| 2022 | 6 | 17 | 196 | Badie | Tyler | BAL | RB | Missouri | from Dolphins via Ravens | ||
| 2022 | 6 | 18 | 197 | Junior | Gregory | JAC | CB | Ouachita Baptist University | from Eagles via Jaguars | ||
| 2022 | 6 | 19 | 198 | Calcaterra | Grant | PHI | TE | SMU | from Steelers via Jaguars via Eagles | ||
| 2022 | 6 | 20 | 199 | Mays | Cade | CAR | G | Tennessee | from Raiders via Panthers | ||
| 2022 | 6 | 21 | 200 | Roberts | Sam | NE | DT | NW Missouri State University | |||
| 2022 | 6 | 22 | 201 | Ingram | Keaontay | ARI | RB | USC | |||
| 2022 | 6 | 23 | 202 | Woods | Mike | CLE | WR | Oklahoma | from Cowboys via Browns | ||
| 2022 | 6 | 24 | 203 | Ebner | Trestan | CHI | RB | Baylor | from Bills via Bears | ||
| 2022 | 6 | 25 | 204 | Jackson | Theo | TEN | CB | Tennessee | |||
| 2022 | 6 | 26 | 205 | Deculus | Austin | HOU | OL | LSU | from Packers via Texans | ||
| 2022 | 6 | 27 | 206 | Henningsen | Matt | DEN | DT | Wisconsin | from Buccaneers via Jets via Eagles via Broncos | ||
| 2022 | 6 | 28 | 207 | Kramer | Doug | CHI | C | Illinois | from 49ers via Jets via Texans via Bears | ||
| 2022 | 6 | 29 | 208 | Heyward | Connor | PIT | TE | Michigan State | from Chiefs via Steelers | ||
| 2022 | 6 | 30 | 209 | Tenuta | Luke | BUF | OT | Virginia Tech | from Bengals via Bills | ||
| 2022 | 6 | 31 | 210 | Hines | Chasen | NE | C | LSU | from Rams via Patriots | ||
| 2022 | 6 | 32 | 211 | Lake | Quentin | LAR | S | UCLA | Compensatory selection | ||
| 2022 | 6 | 33 | 212 | Kendrick | Derion | LAR | CB | Georgia | Compensatory selection | ||
| 2022 | 6 | 34 | 213 | FitzPatrick | John | ATL | TE | Georgia | Compensatory selection | ||
| 2022 | 6 | 35 | 214 | Taylor | Ja'Sir | LAC | DB | Wake Forest | Compensatory selection | ||
| 2022 | 6 | 36 | 215 | Smith | Lecitus | ARI | G | Virginia Tech | Compensatory selection | ||
| 2022 | 6 | 37 | 216 | Brooks | Curtis | IND | DT | Cincinnati | Compensatory selection | ||
| 2022 | 6 | 38 | 217 | Houston | James | DET | LB | Jackson State University | Compensatory selection | ||
| 2022 | 6 | 39 | 218 | Kieft | Ko | TB | TE | Minnesota | Compensatory selection from Rams via Buccaneers | ||
| 2022 | 6 | 40 | 219 | Campbell | Chance | TEN | LB | Mississippi | Compensatory selection | ||
| 2022 | 6 | 41 | 220 | Davis | Kalia | SF | DT | UCF | Compensatory selection | ||
| 2022 | 6 | 42 | 221 | Castro-Fields | Tariq | SF | CB | Penn State | Compensatory selection | ||
| 2022 | 7 | 1 | 222 | Brown | Montaric | JAC | CB | Arkansas | |||
| 2022 | 7 | 2 | 223 | Thomas | Isaiah | CLE | LB | Oklahoma | from Lions via Browns | ||
| 2022 | 7 | 3 | 224 | Goode | Cameron | MIA | LB | California | from Texans via Patriots via Ravens via Dolphins | ||
| 2022 | 7 | 4 | 225 | Robinson | Mark | PIT | LB | Mississippi | from Jets via Steelers | ||
| 2022 | 7 | 5 | 226 | Carter | Ja'Tyre | CHI | G | Southern | from Giants via Bengals via Bears | ||
| 2022 | 7 | 6 | 227 | Muse | Nick | MIN | TE | South Carolina | from Panthers via Raiders via Vikings | ||
| 2022 | 7 | 7 | 228 | Carpenter | Tariq | GRE | S | Georgia Tech | from Bears via Texans via Packers | ||
| 2022 | 7 | 8 | 229 | Melton | Bo | SEA | WR | Rutgers | |||
| 2022 | 7 | 9 | 230 | Paul | Chris | WAS | G | Tulsa | |||
| 2022 | 7 | 10 | 231 | Spector | Baylon | BUF | LB | Clemson | from Falcons via Bills | ||
| 2022 | 7 | 11 | 232 | Hicks | Faion | DEN | CB | Wisconsin | |||
| 2022 | 7 | 12 | 233 | Young | Dareke | SEA | WR | Lenoir Rhyne | from Vikings via Chiefs | ||
| 2022 | 7 | 13 | 234 | Ford | Jonathan | GRE | DT | Miami | from Browns via Lions via Broncos via Packers | ||
| 2022 | 7 | 14 | 235 | Hardy | Daniel | LAR | DE | Montana State | from Ravens via Jaguars via Buccaneers via Rams | ||
| 2022 | 7 | 15 | 236 | Leonard | Deane | LAC | DB | Mississippi | |||
| 2022 | 7 | 16 | 237 | Lucas | Chase | DET | CB | Arizona State | from Saints via Eagles via Lions | ||
| 2022 | 7 | 17 | 238 | Munford | Thayer | LV | OT | Ohio State | from Dolphins via Rams via Raiders | ||
| 2022 | 7 | 18 | 239 | Thomas | Rodney | IND | DB | Yale | |||
| 2022 | 7 | 19 | 240 | Holmes | Christian | WAS | CB | Oklahoma State | from Eagles via Colts via Commanders | ||
| 2022 | 7 | 20 | 241 | Oladokun | Chris | PIT | QB | South Dakota State | |||
| 2022 | 7 | 21 | 242 | Barnes | Kalon | CAR | CB | Baylor | from Patriots via Dolphins via Panthers | ||
| 2022 | 7 | 22 | 243 | Watson | Jaylen | KAN | CB | Washington State | from Raiders via Patriots via Chiefs | ||
| 2022 | 7 | 23 | 244 | Matthew | Christian | ARI | DB | Valdosta State | |||
| 2022 | 7 | 24 | 245 | Stueber | Andrew | NE | OT | Michigan | from Cowboys via Texans via Patriots | ||
| 2022 | 7 | 25 | 246 | Deaton | Dawson | CLE | C | Texas Tech | from Bills via Browns | ||
| 2022 | 7 | 26 | 247 | Thompson | Skylar | MIA | QB | Kansas State | from Titans via Dolphins | ||
| 2022 | 7 | 27 | 248 | Anthony | Andre | TB | LB | LSU | |||
| 2022 | 7 | 28 | 249 | Walker | Rasheed | GRE | OT | Penn State | |||
| 2022 | 7 | 29 | 250 | Brown | Brittain | LV | RB | UCLA | from 49ers via Broncos via Vikings via Raiders | ||
| 2022 | 7 | 30 | 251 | Pacheco | Isiah | KAN | RB | Rutgers | |||
| 2022 | 7 | 31 | 252 | Gunter | Jeffrey | CIN | LB | Coastal Carolina | |||
| 2022 | 7 | 32 | 253 | Yeast | Russ | LAR | S | Kansas State | |||
| 2022 | 7 | 33 | 254 | Hicks | Elijah | CHI | DB | California | Compensatory selection from Chargers via Bears | ||
| 2022 | 7 | 34 | 255 | Gill | Trenton | CHI | P | N.C. State | Compensatory selection from Chargers via Bears | ||
| 2022 | 7 | 35 | 256 | Luketa | Jesse | ARI | LB | Penn State | Compensatory selection | ||
| 2022 | 7 | 36 | 257 | Hayes | Marquis | ARI | G | Oklahoma | Compensatory selection | ||
| 2022 | 7 | 37 | 258 | Toure | Samori | GRE | WR | Nebraska | Compensatory selection | ||
| 2022 | 7 | 38 | 259 | Johnson | Nazeeh | KAN | CB | Marshall | Compensatory selection | ||
| 2022 | 7 | 39 | 260 | Horvath | Zander | LAC | FB | Purdue | Compensatory selection | ||
| 2022 | 7 | 40 | 261 | Arcuri | A.J. | LAR | OT | Michigan State | Compensatory selection from Buccaneers via Rams | ||
| 2022 | 7 | 41 | 262 | Purdy | Brock | SF | QB | Iowa State | Compensatory selection | ||